European police today claimed they had uncovered an Asian betting syndicate responsible for more than 380 suspicious games, including Word Cup and European Championship qualifiers and two Champions League games.
Europol says up to 425 officials, players and criminals are thought to have been involved in the operation which police say made millions of pounds worth of profits.
Rob Wainwright, director of Europol, said: "This is the work of a suspected organised crime syndicate based in Asia and operated with criminal networks around Europe.
"It is clear to us this is the biggest-ever investigation into suspected match-fixing in Europe. It has yielded major results which we think have uncovered a big problem for the integrity of football in Europe.
"We have uncovered an extensive criminal network."
Police would not reveal which game in England was under suspicion because of "ongoing judicial proceedings", but confirmed it was played in the last three or four years.
Wainwright said: "The focus has been on other countries, not the United Kingdom. However we were surprised by the scale generally of the criminal enterprise and just how widespread it was.
Rob Wainwright reveals Europol's findings at a press conference in The Hague "It would be naive and complacent of those in the UK to think such a criminal conspiracy does not involved the English game and all the football in Europe."
He said it uncovered 8 million euros (£6.9 million) in betting profits and 2 million euros (£1.7 million) in bribes to players and officials and has already led to several prosecutions.
"This is a sad day for European football," Mr Wainwright added.
He said a Singapore-based criminal network was involved in the match fixing, spending up to 100,000 euros (£86,000) per match to bribe players and officials.
He refused to identify any of the suspects, players or matches involved, citing ongoing investigations.
He said while many fixed matches were already known, the Europol investigation lifted the lid on the widespread involvement or organised crime in rigging games.
"This is the first time we have established substantial evidence that organised crime is now operating in the world of football," he said.
